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6-fluoroquinolin-5-amine; CAS No.: 1251032-63-9; 6-fluoroquinolin-5-amine. PROPERTIES: 6-fluoroquinolin-5-amine is a crystalline compound with molecular formula C9H6FNN2. It has a melting point between 145-150 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from strong oxidizing agents. Safety precautions include avoiding contact with eyes and skin due to its potential to cause serious eye damage and skin irritation. APPLICATIONS: This fluorinated quinoline derivative is employed in the development of antimicrobial agents. The amine group at position 5 allows for glycosylation, creating fluoroquinolone antibiotics with enhanced antibacterial spectra as reported in pharmaceutical chemistry journals. In bioanalytical applications, 6-fluoroquinolin-5-amine serves as a fluorescent probe for detecting specific metal ions. According to analytical chemistry research, the quinoline scaffold's fluorescence is quenched upon metal coordination, enabling sensitive detection methods with limits approaching nanomolar concentrations.