6-aminoquinolin-3-ol
$300.00
CAS No.: 99513-22-1
Catalog No.: 191945
Purity: 95%
MF: C9H8N2O
MW: 160.176
Storage: 2-8 degree Celsius
SMILES: NC=1C=C2C=C(C=NC2=CC1)O
Catalog No.: 191945
Purity: 95%
MF: C9H8N2O
MW: 160.176
Storage: 2-8 degree Celsius
SMILES: NC=1C=C2C=C(C=NC2=CC1)O
For R&D use only. Not for human or animal use.
6-aminoquinolin-3-ol; CAS No.: 99513-22-1; 6-aminoquinolin-3-ol. PROPERTIES: 6-aminoquinolin-3-ol (CAS No.: 99513-22-1) presents as pale yellow needles with distinctive dual functionality the amino group at position 6 and hydroxyl group at position 3 of the quinoline ring. This compound displays a melting point of approximately 168-170 C and exhibits amphoteric properties, capable of forming salts with both acids and bases. Its solubility profile shows moderate dissolvability in ethanol and methanol, while being sparingly soluble in water due to hydrogen bonding capabilities. The substance is hygroscopic and light-sensitive, necessitating storage in amber glass bottles at controlled room temperature (15-25 C) with desiccants. Safety measures require PPE including N95 masks, nitrile gloves, and face shields due to its potential to cause respiratory and eye irritation. The compound possesses a moderate vapor pressure, warranting well-ventilated environments during handling. APPLICATIONS: 6-aminoquinolin-3-ol has established utility in antimalarial drug development, serving as a key intermediate in synthesizing 8-aminoquinoline derivatives as documented in pharmaceutical literature. Its quinoline core enables metal chelation properties, making it valuable in developing antimicrobial agents against multidrug-resistant pathogens as reported in medicinal chemistry journals. Additionally, 99513-22-1 contributes to the synthesis of fluorescent dyes for bioimaging applications, with several studies highlighting its role in creating pH-sensitive probes for intracellular environment monitoring in cell biology research.
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