5-methyl-1,2,3,4-tetrahydroquinoline hydrochloride; CAS No.: 861368-85-6; 5-methyl-1,2,3,4-tetrahydroquinoline hydrochloride. PROPERTIES: 5-methyl-1,2,3,4-tetrahydroquinoline hydrochloride is a crystalline hydrochloride salt with molecular formula C8H11N {HCl, having a molar mass of approximately 155.64 g/mol. It demonstrates good water solubility and moderate solubility in ethanol. Melting point determinations typically yield values between 188-192 C. Proper storage requires maintaining in tightly sealed containers at room temperature, protected from moisture and strong oxidizing agents. Safety considerations identify it as causing skin irritation and serious eye damage. Precautionary measures recommend using explosion-proof equipment and providing adequate sanitation facilities. APPLICATIONS: This compound serves as a valuable intermediate in the synthesis of antidepressant and anxiolytic medications. Its methyl group at position 5 enhances metabolic stability in bioactive molecules. In medicinal chemistry research, it supports the development of beta-blockers through selective derivatization pathways. The compound also contributes to materials science applications in fluorescent probe development for detecting reactive oxygen species, with methodologies published in Bioorganic & Medicinal Chemistry and related pharmaceutical patents, illustrating its significance in psychiatric medication design and analytical chemistry tools.