5-bromoquinolin-7-amine
$450.00
CAS No.: 1934465-17-4
Catalog No.: 191979
Purity: 95%
MF: C9H7BrN2
MW: 223.073
Storage: 2-8 degree Celsius
SMILES: BrC1=C2C=CC=NC2=CC(=C1)N
Catalog No.: 191979
Purity: 95%
MF: C9H7BrN2
MW: 223.073
Storage: 2-8 degree Celsius
SMILES: BrC1=C2C=CC=NC2=CC(=C1)N
For R&D use only. Not for human or animal use.
5-bromoquinolin-7-amine; CAS No.: 1934465-17-4;5-bromoquinolin-7-amine. PROPERTIES: 5-bromoquinolin-7-amine is a halogenated quinoline amine with molecular formula C9H6BrN2. This crystalline material typically appears as brownish powder and has a melting point between 190-195 C. The molecule contains a quinoline core with a bromine atom at position 5 and an amine group at position 7. The 5-bromoquinolin-7-amine exhibits basic character due to the amine group, with a pKa value around 4.8. It demonstrates limited solubility in water but dissolves well in polar aprotic solvents like DMSO. Proper storage requires keeping in a tightly sealed container with inert atmosphere, stored below 10 C to prevent oxidative degradation. Safety precautions include using N95 respiratory protection and chemical-resistant gloves, as the compound may cause respiratory irritation and skin burns. According to EU safety regulations, it carries H314 and H335 hazard statements for causing severe skin burns and respiratory tract irritation. APPLICATIONS: The 5-bromoquinolin-7-amine molecule serves as a valuable intermediate in the synthesis of quinoline-based antitubercular agents, as reported in medicinal chemistry research focusing on infectious disease treatments. The bromo substituent provides a site for further functionalization via coupling reactions. Additionally, 5-bromoquinolin-7-amine derivatives have been investigated for their potential as fluorescent probes for bioimaging applications, as described in analytical chemistry publications. The compound's ability to form coordination complexes with metal ions has also made it useful in developing chemical sensors for metal detection, as documented in materials science studies emphasizing selective ion recognition.
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