4-methoxyquinoline-8-carboxylic acid
$300.00
CAS No.: 2479322-34-2
Catalog No.: 192347
Purity: 95%
MF: C11H9NO3
MW: 203.197
Storage: 2-8 degree Celsius
SMILES: COC1=CC=NC2=C(C=CC=C12)C(=O)O
Catalog No.: 192347
Purity: 95%
MF: C11H9NO3
MW: 203.197
Storage: 2-8 degree Celsius
SMILES: COC1=CC=NC2=C(C=CC=C12)C(=O)O
4-methoxyquinoline-8-carboxylic acid; CAS No.: 2479322-34-2; 4-methoxyquinoline-8-carboxylic acid. PROPERTIES: 4-methoxyquinoline-8-carboxylic acid is a crystalline substance with molecular formula C10H8NO3. It has a melting point of approximately 230-235 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This methoxy-substituted quinoline carboxylic acid is used in the development of anticancer prodrugs. The methoxy group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 4-methoxyquinoline-8-carboxylic acid serves as a building block for creating photoaffinity labels. According to biochemical journals, the quinoline scaffold provides a fluorescent signal while the carboxylic acid group enables photoinduced cross-linking with target proteins.
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