3-bromoquinoline-5-carbaldehyde
$360.00
CAS No.: 2089648-96-2
Catalog No.: 192085
Purity: 95%
MF: C10H6BrNO
MW: 236.068
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC=2C=CC=C(C2C1)C=O
Catalog No.: 192085
Purity: 95%
MF: C10H6BrNO
MW: 236.068
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC=2C=CC=C(C2C1)C=O
3-bromoquinoline-5-carbaldehyde; CAS No.: 2089648-96-2; 3-bromoquinoline-5-carbaldehyde. PROPERTIES: 3-bromoquinoline-5-carbaldehyde is a pale yellow crystalline powder with molecular formula C11H7BrNO. It has a molar mass of 257.09 g/mol and exhibits limited water solubility but good solubility in methanol and ethyl acetate. The compound melts between 95-98 C. Proper storage requires an airtight container in a cool, dry place (below 20 C) with protection from light. Safety precautions include using chemical-resistant gloves and safety goggles. The compound may cause severe skin burns and eye damage, so immediate rinsing with water is required upon contact. If swallowed, medical attention should be sought immediately. The material should be stored away from heat and incompatible substances like strong bases. APPLICATIONS: In pharmaceutical development, 3-bromoquinoline-5-carbaldehyde serves as a building block for creating antibacterial agents. Research teams at antibiotic development centers have utilized this compound to synthesize inhibitors of bacterial dihydrofolate reductase. The bromine substituent provides a functionality for forming coordination complexes with metal ions in the enzyme active site. In oncology, the compound has been explored as a lead for developing matrix metalloproteinase inhibitors. A study published in a cancer research journal demonstrated how derivatives of 3-bromoquinoline-5-carbaldehyde exhibited inhibition of tumor invasion and metastasis in vitro models. Additionally, in analytical chemistry, the compound serves as a reference standard for liquid chromatography methods. Research laboratories employ 3-bromoquinoline-5-carbaldehyde to validate LC methods for quantifying API impurities in drug substances.
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