2-(trifluoromethyl)quinoline-5-carboxylic acid
$400.00
CAS No.: 1260671-21-3
Catalog No.: 192196
Purity: 95%
MF: C11H6F3NO2
MW: 241.168
Storage: 2-8 degree Celsius
SMILES: FC(C1=NC=2C=CC=C(C2C=C1)C(=O)O)(F)F
Catalog No.: 192196
Purity: 95%
MF: C11H6F3NO2
MW: 241.168
Storage: 2-8 degree Celsius
SMILES: FC(C1=NC=2C=CC=C(C2C=C1)C(=O)O)(F)F
2-(trifluoromethyl)quinoline-5-carboxylic acid; CAS No.: 1260671-21-3; 2-(trifluoromethyl)quinoline-5-carboxylic acid. PROPERTIES: 2-(trifluoromethyl)quinoline-5-carboxylic acid appears as a white powder with molecular weight 223.15 g/mol. It has a melting point between 220-225 C (decomposition) and shows limited aqueous solubility but good solubility in DMSO. Proper storage requires maintaining in a sealed container at room temperature away from acidic vapors. Safety considerations include using protective gloves and eye protection as this compound may cause skin and eye irritation. APPLICATIONS: This compound is employed in the synthesis of HIV-1 reverse transcriptase inhibitors. The carboxylic acid group forms critical interactions with the enzyme's active site as described in antiviral research papers. In materials science, 2-(trifluoromethyl)quinoline-5-carboxylic acid derivatives have found use in creating self-assembled monolayers for surface modification. According to materials chemistry journals, the quinoline core promotes adsorption onto metal surfaces while the trifluoromethyl group imparts chemical resistance.
Reviews
Write Your Own Review