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2-(trifluoromethyl)quinolin-7-amine; CAS No.: 2241594-48-7; 2-(trifluoromethyl)quinolin-7-amine. PROPERTIES: 2-(trifluoromethyl)quinolin-7-amine is a pale yellow solid with molecular formula C9H6F3N2. It has a melting point between 120-125 C and shows solubility in polar organic solvents while being practically insoluble in water. Proper storage involves maintaining under nitrogen atmosphere at 5-15 C to prevent oxidation. Safety considerations include avoiding contact with strong acids and using protective equipment as this compound may cause serious eye damage. APPLICATIONS: This trifluoromethyl-substituted quinoline amine is utilized in the synthesis of kinase inhibitors. The amine group provides critical interactions with the enzyme's active site as described in cancer research literature. In materials science, 2-(trifluoromethyl)quinolin-7-amine derivatives have found application in creating electron-transport materials for organic photovoltaics. According to materials chemistry journals, the electron-withdrawing trifluoromethyl group improves charge transport properties while the quinoline scaffold provides structural rigidity.