2-bromoquinoline-4-carboxylic acid
$200.00
CAS No.: 15733-87-6
Catalog No.: 196017
Purity: 95%
MF: C10H6BrNO2
MW: 252.067
Storage: 2-8 degree Celsius
SMILES: BrC1=NC2=CC=CC=C2C(=C1)C(=O)O
Catalog No.: 196017
Purity: 95%
MF: C10H6BrNO2
MW: 252.067
Storage: 2-8 degree Celsius
SMILES: BrC1=NC2=CC=CC=C2C(=C1)C(=O)O
2-bromoquinoline-4-carboxylic acid; CAS No.: 15733-87-6; 2-bromoquinoline-4-carboxylic acid. PROPERTIES: 2-bromoquinoline-4-carboxylic acid presents as a white crystalline powder with molecular formula C9H5BrNO2, possessing a molar mass of approximately 259.05 g/mol. It shows limited water solubility but dissolves in hot ethanol and dimethylformamide. Thermal analysis indicates melting point in the range of 210-214 C with potential decomposition. Storage requirements mandate tightly sealed containers in a cool, dry place away from alkaline materials. Safety precautions highlight potential to cause serious eye damage and skin irritation. Proper handling involves using corrosion-resistant equipment and providing adequate sanitation facilities. APPLICATIONS: This compound serves as a critical intermediate in the synthesis of HIV integrase inhibitors, leveraging its carboxylic acid functionality for constructing bioactive scaffolds. In medicinal chemistry, it facilitates the development of antibacterial agents targeting multidrug-resistant pathogens through selective derivatization. The bromine substituent at position 2 enables Suzuki coupling reactions essential for constructing complex heterocycles. Applications are documented in Antimicrobial Agents and Chemotherapy and related pharmaceutical patents, underscoring its importance in addressing antimicrobial resistance and viral infections through innovative therapeutic agent design.
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