2-(4-fluorophenyl)-2,3-dihydroquinolin-4(1H)-one
$400.00
CAS No.: 155370-03-9
Catalog No.: 196040
Purity: 95%
MF: C15H12FNO
MW: 241.265
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C(C=C1)C1NC2=CC=CC=C2C(C1)=O
Catalog No.: 196040
Purity: 95%
MF: C15H12FNO
MW: 241.265
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C(C=C1)C1NC2=CC=CC=C2C(C1)=O
2-(4-fluorophenyl)-2,3-dihydroquinolin-4(1H)-one; CAS No.: 155370-03-9; 2-(4-fluorophenyl)-2,3-dihydroquinolin-4(1H)-one. PROPERTIES: 2-(4-fluorophenyl)-2,3-dihydroquinolin-4(1H)-one is a crystalline solid with molecular formula C15H10FN2O, having a molar mass of approximately 257.25 g/mol. It demonstrates limited water solubility but good solubility in DMSO and dimethylformamide. Melting point determinations typically yield values between 195-199 C. Proper storage requires maintaining in airtight containers at temperatures below 20 C, protected from light and moisture. Safety considerations identify it as causing skin irritation and serious eye damage. Precautionary measures recommend using explosion-proof equipment and providing adequate hygiene facilities. APPLICATIONS: This compound serves as a valuable intermediate in the synthesis of kinase inhibitors, particularly those targeting fibroblast growth factor receptors (FGFRs). Its fluorinated phenyl group at position 2 enables selective modification for constructing bioactive molecules. In medicinal chemistry research, it supports the development of anticancer agents through controlled derivatization pathways. The compound also contributes to materials science applications in photostabilizer development for polymer systems, with methodologies published in Journal of Medicinal Chemistry and related pharmaceutical patents, illustrating its significance in oncology and materials protection innovations.
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