1-bromoisoquinoline-6-carboxylic acid
$300.00
CAS No.: 1368330-08-8
Catalog No.: 192247
Purity: 95%
MF: C10H6BrNO2
MW: 252.067
Storage: 2-8 degree Celsius
SMILES: BrC1=NC=CC2=CC(=CC=C12)C(=O)O
Catalog No.: 192247
Purity: 95%
MF: C10H6BrNO2
MW: 252.067
Storage: 2-8 degree Celsius
SMILES: BrC1=NC=CC2=CC(=CC=C12)C(=O)O
1-bromoisoquinoline-6-carboxylic acid; CAS No.: 1368330-08-8; 1-bromoisoquinoline-6-carboxylic acid. PROPERTIES: 1-bromoisoquinoline-6-carboxylic acid is a crystalline substance with molecular formula C9H5BrO2N. It has a melting point of approximately 200-205 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated isoquinoline carboxylic acid is used in the development of anticancer prodrugs. The carboxylic acid group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 1-bromoisoquinoline-6-carboxylic acid serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the bromine group enables photoinduced cross-linking with target proteins.
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