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1-(2,4-dimethylquinolin-3-yl)ethanone; CAS No.: 943825-10-3; This quinolinyl ketone from ChemShuttle acts as a chem block for HDAC inhibitor development. The acetyl group chelates catalytic zinc ions in histone deacetylases. The company s chemical synthesis company expertise includes hydroxamic acid derivatization for improved binding affinity.