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(1,2,3,4-tetrahydroisoquinolin-1-yl)methanol hydrochloride; CAS No.: 17163-39-2; (1,2,3,4-tetrahydroisoquinolin-1-yl)methanol hydrochloride. PROPERTIES: (1,2,3,4-Tetrahydroisoquinolin-1-yl)methanol hydrochloride appears as an off-white powder with a characteristic amine salt odor. The compound exhibits high water solubility and typical behavior of quaternary ammonium compounds in chromatographic systems. Thermal analysis shows melting point depression in the presence of moisture necessitating anhydrous conditions during storage. Safety protocols recommend avoiding contact with eyes and skin due to moderate corrosive potential as per GHS classification P305+P351+P338. APPLICATIONS: (1,2,3,4-Tetrahydroisoquinolin-1-yl)methanol hydrochloride serves as an intermediate in the preparation of beta-2 adrenergic agonists detailed in respiratory pharmacology research. Its isoquinoline framework enables construction of alkaloid-inspired libraries useful in CNS drug discovery as reported in neurochemistry journals. Furthermore, the compound functions as a chiral auxiliary in asymmetric synthesis applications described in organic catalysis literature.