6-bromo-2-methoxyquinazoline
$300.00
CAS No.: 1260785-32-7
Catalog No.: 192295
Purity: 95%
MF: C9H7BrN2O
MW: 239.072
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C2C=NC(=NC2=CC1)OC
Catalog No.: 192295
Purity: 95%
MF: C9H7BrN2O
MW: 239.072
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C2C=NC(=NC2=CC1)OC
6-bromo-2-methoxyquinazoline; CAS No.: 1260785-32-7; 6-bromo-2-methoxyquinazoline. PROPERTIES: 6-bromo-2-methoxyquinazoline is a crystalline compound with molecular formula C10H7BrN3O. It has a melting point between 190-195 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated, methoxy-substituted quinazoline is used in the development of anticancer prodrugs. The bromine substituent serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 6-bromo-2-methoxyquinazoline serves as a building block for creating photoaffinity labels. According to biochemical journals, the quinazoline scaffold provides a fluorescent signal while the bromine group enables photoinduced cross-linking with target proteins.
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