4-chloro-6-nitroquinazoline hydrochloride; CAS No.: 220488-24-4; 4-chloro-6-nitroquinazoline hydrochloride. PROPERTIES: 4-chloro-6-nitroquinazoline hydrochloride is a crystalline solid. Its molecular formula is C8H5ClN3O2 {HCl, and the molecular weight is approximately 245.06 g/mol. The compound has a melting point of approximately 220-222 C. It is moderately soluble in water and commonly used in the form of its hydrochloride salt. For proper storage, it should be kept in a sealed container at room temperature, away from heat and direct sunlight. As a compound containing a quinazoline ring, a chloro group, and a nitro group, it may exhibit certain reactivity and stability. When handling it, protective gloves and eye protection should be worn. In case of accidental ingestion, medical attention should be sought immediately. APPLICATIONS: In organic synthesis, 4-chloro-6-nitroquinazoline serves as a valuable intermediate. The chloro group can undergo various reactions such as substitution and coupling. The nitro group can be reduced to an amine group. In the pharmaceutical industry, derivatives of this compound can be explored as potential drug candidates. For example, in the development of certain anticancer drugs, the structure of 4-chloro-6-nitroquinazoline can be modified to enhance the drug's ability to target cancer cells and improve its therapeutic index (as reported in medicinal chemistry journals). Additionally, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in catalysis and sensing (as noted in organic chemistry research papers).