2-cyclopropyl-6-fluoroquinazolin-4(3H)-one
$300.00
CAS No.: 1252134-65-8
Catalog No.: 192508
Purity: 95%
MF: C11H9FN2O
MW: 204.204
Storage: 2-8 degree Celsius
SMILES: C1(CC1)C1=NC2=CC=C(C=C2C(N1)=O)F
Catalog No.: 192508
Purity: 95%
MF: C11H9FN2O
MW: 204.204
Storage: 2-8 degree Celsius
SMILES: C1(CC1)C1=NC2=CC=C(C=C2C(N1)=O)F
2-cyclopropyl-6-fluoroquinazolin-4(3H)-one; CAS No.: 1252134-65-8; 2-cyclopropyl-6-fluoroquinazolin-4(3H)-one. PROPERTIES: 2-cyclopropyl-6-fluoroquinazolin-4(3H)-one is a crystalline compound with molecular formula C11H9FN2O. It has a melting point between 190-195 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its flammable nature. APPLICATIONS: This cyclopropyl, fluorinated quinazolinone is employed in the development of kinase inhibitors. The cyclopropyl group provides unique binding affinity as described in cancer research literature. In medicinal chemistry, 2-cyclopropyl-6-fluoroquinazolin-4(3H)-one serves as a key intermediate for creating central nervous system agents. According to pharmaceutical patents, the fluorine substituent enhances blood-brain barrier penetration while the cyclopropyl group offers metabolic stability.
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