![methyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/1/7/171654_2.jpg)
![ethyl 3-bromopyrrolo[1,2-a]pyrimidine-6-carboxylate](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/1/9/193064_2.jpg)
3-bromopyrrolo[1,2-a]pyrimidine-6-carboxylic acid
$300.00
CAS No.: 1823918-84-8
Catalog No.: 193063
Purity: 95%
MF: C8H5BrN2O2
MW: 241.044
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC=2N(C1)C(=CC2)C(=O)O
Catalog No.: 193063
Purity: 95%
MF: C8H5BrN2O2
MW: 241.044
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NC=2N(C1)C(=CC2)C(=O)O
3-bromopyrrolo[1,2-a]pyrimidine-6-carboxylic acid; CAS No.: 1823918-84-8; 3-bromopyrrolo[1,2-a]pyrimidine-6-carboxylic acid. PROPERTIES: This compound presents as a white crystalline solid with molecular formula C8H5BrN3O2 and a molecular weight of 257.05 g/mol. It demonstrates a melting point in the range of 152-156 C and shows moderate solubility in common organic solvents like dimethylformamide and dimethyl sulfoxide. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 3-bromopyrrolo[1,2-a]pyrimidine-6-carboxylic acid may release toxic fumes upon heating. The bromo group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 3-bromopyrrolo[1,2-a]pyrimidine-6-carboxylic acid serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its bromo substituent enables participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrrolopyrimidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
Reviews
Write Your Own Review