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2-chloro-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one; CAS No.: 335654-08-5; 2-Chloro-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one from our purine analog series demonstrates expertise in fused diazine synthesis. The chloro substituent enables cross-coupling reactions for kinase inhibitor development. As a custom chemical synthesis company, we optimize Buchwald-Hartwig conditions for nitrogen-rich heterocycles. The partially saturated ring system reduces planarity while maintaining hydrogen bonding capacity. Our production process includes strict control of ring-opening side reactions during chlorination steps.