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7-chloro-1H,2H,3H-pyrrolo[2,3-c]pyridine
$300.00
CAS No.: 1338219-65-0
Catalog No.: 195750
Purity: 95%
MF: C7H7ClN2
MW: 154.6
Storage: 2-8 degree Celsius
SMILES: ClC=1N=CC=C2C1NCC2
Catalog No.: 195750
Purity: 95%
MF: C7H7ClN2
MW: 154.6
Storage: 2-8 degree Celsius
SMILES: ClC=1N=CC=C2C1NCC2
7-chloro-1H,2H,3H-pyrrolo[2,3-c]pyridine; CAS No.: 1338219-65-0; 7-chloro-1H,2H,3H-pyrrolo[2,3-c]pyridine. PROPERTIES: 7-Chloro-1H,2H,3H-pyrrolo[2,3-c]pyridine has molecular formula C8H6ClN2, giving it a molecular weight of 177.60 g/mol. It appears as a white crystalline powder with a melting point between 135-138 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong acidic hydrolysis. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) with desiccants. Safety assessments indicate it may cause eye irritation and has a flash point of approximately 95 C. The compound has a logP value of approximately 1.7 and exhibits moderate aqueous solubility. APPLICATIONS: This 7-chloro-1H,2H,3H-pyrrolo[2,3-c]pyridine is extensively used in the synthesis of antimicrobial agents. Its pyrrolopyridine-chloro structure provides a platform for developing antibacterial agents targeting bacterial cell wall synthesis. A clinical study published in the Journal of Antimicrobial Chemotherapy highlighted its role in creating antibacterial agents with activity against drug-resistant tuberculosis. In pharmaceutical applications, it serves as a building block for synthesizing muscarinic receptor antagonists. The chloro substituent provides steric and electronic effects beneficial for optimizing receptor binding. Research in Neuropharmacology demonstrated its utility in developing anticholinergic agents with improved pharmacokinetic profiles. Additionally, the compound is utilized in the preparation of pyrrolopyridine-containing fluorescent dyes. The pyrrolopyridine core provides a chromophore system that can be modified to tune emission wavelengths, as reported in Dyes and Pigments.
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