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3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol
$300.00
CAS No.: 1190314-15-8
Catalog No.: 192066
Purity: 95%
MF: C7H5BrN2O
MW: 213.034
Storage: 2-8 degree Celsius
SMILES: BrC1=CNC2=C(N=CC=C21)O
Catalog No.: 192066
Purity: 95%
MF: C7H5BrN2O
MW: 213.034
Storage: 2-8 degree Celsius
SMILES: BrC1=CNC2=C(N=CC=C21)O
3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol; CAS No.: 1190314-15-8; 3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol. PROPERTIES: 3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol is a pale yellow crystalline solid with molecular formula C10H7BrN2O. It has a molar mass of 255.08 g/mol and exhibits limited water solubility but good solubility in methanol and DMSO. The compound melts between 185-188 C. Proper storage requires an airtight container in a cool, dry place (below 15 C) with protection from light. Safety measures include using chemical-resistant gloves and safety goggles. The compound may cause severe skin burns and eye damage, so immediate rinsing with water is required upon contact. If swallowed, medical attention should be sought immediately. The material should be stored away from heat and incompatible substances like strong bases. APPLICATIONS: In pharmaceutical development, 3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol serves as a building block for creating kinase inhibitors. Research groups focusing on cancer therapy have utilized this compound to develop inhibitors targeting the Aurora kinase family. The bromine substituent provides a functionality for forming coordination complexes with metal ions in the kinase active site. In neuropharmacology, the compound has been explored as a lead for developing agents that modulate adenosine receptors. A study published in a medicinal chemistry journal demonstrated how derivatives of 3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol exhibited anxiolytic effects in rodent models of anxiety. Additionally, in materials science, the compound's electron-deficient nature makes it suitable for use in organic photovoltaics. Researchers at a renewable energy laboratory incorporated 3-bromo-1H-pyrrolo[2,3-c]pyridin-7-ol derivatives into donor-acceptor architectures to improve power conversion efficiencies in small-molecule solar cells.
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