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6-phenyl-5H-pyrrolo[2,3-b]pyrazine
$350.00
CAS No.: 78605-10-4
Catalog No.: 196486
Purity: 95%
MF: C12H9N3
MW: 195.225
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=CC=2C(=NC=CN2)N1
Catalog No.: 196486
Purity: 95%
MF: C12H9N3
MW: 195.225
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=CC=2C(=NC=CN2)N1
6-phenyl-5H-pyrrolo[2,3-b]pyrazine; CAS No.: 78605-10-4; 6-phenyl-5H-pyrrolo[2,3-b]pyrazine. PROPERTIES: 6-phenyl-5H-pyrrolo[2,3-b]pyrazine appears as a yellow to orange crystalline solid. Its molecular formula is C13H7N3, corresponding to a molecular weight of 209.21 g/mol. The compound exhibits moderate solubility in common organic solvents such as dimethylformamide and dimethyl sulfoxide, but is sparingly soluble in water. It has a melting point typically ranging from 210-215 C and is stable under normal laboratory conditions when stored properly. Recommended storage involves keeping the material in a tightly sealed container at room temperature (15-25 C), preferably in a cool, dry, and dark environment away from heat sources and moisture. The compound is light-sensitive to some extent and should be protected from prolonged exposure to direct sunlight. Safety precautions include wearing appropriate personal protective equipment, including chemical-resistant gloves, eye protection, and lab coats when handling the material. In case of skin contact, washing with soap and water is advised, and eye contact requires thorough rinsing with water for at least 15 minutes followed by medical attention if irritation persists. The compound should be handled in well-ventilated areas to minimize inhalation risks. APPLICATIONS: 6-phenyl-5H-pyrrolo[2,3-b]pyrazine serves as a valuable building block in heterocyclic chemistry, particularly in the synthesis of complex polycyclic frameworks. Its unique electronic properties make it suitable for applications in materials science, where derivatives have been explored for their potential in organic photovoltaics and as components in light-emitting diodes, as reported in materials chemistry journals. In pharmaceutical research, the compound has been utilized as a core structure in the development of novel kinase inhibitors and as a scaffold for anticancer agents targeting specific oncogenic pathways. The pyrrolopyrazine framework provides a suitable platform for the design of bioisosteres and in the development of enzyme inhibitors with improved pharmacokinetic profiles. Additionally, 6-phenyl-5H-pyrrolo[2,3-b]pyrazine finds application in agrochemical research for the development of herbicides and fungicides, though this application is beyond the current scope. Its utility extends to analytical chemistry, where it serves as a reference compound for spectral databases and as a starting material for custom syntheses in specialized laboratories focusing on heterocyclic chemistry and medicinal applications.
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