tert-butyl (3R,4R)-4-hydroxypyrrolidin-3-ylcarbamate hydrochloride
$275.00
CAS No.: 1820575-70-9
Catalog No.: 193003
Purity: 95%
MF: C9H19ClN2O3
MW: 238.715
Storage: 2-8 degree Celsius
SMILES: Cl.O[C@H]1[C@@H](CNC1)NC(OC(C)(C)C)=O
Catalog No.: 193003
Purity: 95%
MF: C9H19ClN2O3
MW: 238.715
Storage: 2-8 degree Celsius
SMILES: Cl.O[C@H]1[C@@H](CNC1)NC(OC(C)(C)C)=O
tert-butyl (3R,4R)-4-hydroxypyrrolidin-3-ylcarbamate hydrochloride; CAS No.: 1820575-70-9; tert-butyl (3R,4R)-4-hydroxypyrrolidin-3-ylcarbamate hydrochloride. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C10H18N2O3 {HCl and a molecular weight of 244.72 g/mol. It exhibits a melting point in the range of 168-172 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as tert-butyl (3R,4R)-4-hydroxypyrrolidin-3-ylcarbamate hydrochloride may cause skin irritation. The hydroxyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, tert-butyl (3R,4R)-4-hydroxypyrrolidin-3-ylcarbamate hydrochloride serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrrolidine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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