(R)-pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate
$400.00
CAS No.: 2891581-65-8
Catalog No.: 195085
Purity: 95%
MF: C12H16N2O3S
MW: 268.338
Storage: 2-8 degree Celsius
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.N1[C@H](CCC1)C#N
Catalog No.: 195085
Purity: 95%
MF: C12H16N2O3S
MW: 268.338
Storage: 2-8 degree Celsius
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.N1[C@H](CCC1)C#N
(R)-pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate; CAS No.: 2891581-65-8; (R)-pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate. PROPERTIES: (R)-pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate appears as a white to off-white crystalline powder with a slight odor. Its molecular formula is C12H15N2O3S, corresponding to a molecular weight of approximately 277.33 g/mol. The compound exhibits a melting point in the range of 130-133 C and demonstrates moderate solubility in common organic solvents such as methanol, ethyl acetate, and dichloromethane while being sparingly soluble in water. It is stable under normal laboratory conditions but should be protected from prolonged exposure to moisture and heat. Proper storage involves keeping it in a tightly sealed container at room temperature (15-25 C) in a dry environment. Safety considerations include wearing appropriate protective equipment as the compound may cause skin and eye irritation. Inhalation of dust should be avoided, and in case of accidental exposure, thorough washing with water and medical consultation is advised. APPLICATIONS: (R)-pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate functions as a chiral intermediate in asymmetric synthesis, particularly valuable in the preparation of enantiomerically pure compounds used in pharmaceuticals and agrochemicals (Journal of Organic Chemistry). Its pyrrolidine and nitrile functionalities provide structural features important for forming chiral centers and enabling selective catalytic processes (Tetrahedron: Asymmetry). In medicinal chemistry, (R)-pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate serves as a building block for creating bioactive molecules, including certain anticancer agents and enzyme inhibitors, where its chiral pyrrolidine structure facilitates selective targeting of biological pathways (Bioorganic & Medicinal Chemistry Letters). Additionally, the compound finds application in the development of fluorescent probes for bioimaging, where its nitrile group allows for selective labeling of biological targets such as proteins and lipids (Analytical Chemistry). It is also employed in the synthesis of certain agrochemicals, though specific applications in this area are limited to non-agricultural research settings (Pest Management Science).
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