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(R)-2-(pyrrolidin-3-yloxy)pyridine dihydrochloride; CAS No.: 1260613-92-0; This pyridyl pyrrolidine dihydrochloride highlights our building blocks for opioid receptor research. The (R)-configured ether linkage and dihydrochloride salt enhance -receptor selectivity. Our Mitsunobu reaction achieves complete stereochemical control. The product enables development of peripherally-restricted analgesics with reduced addiction potential.