(R)-1-tert-butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate
$300.00
CAS No.: 128811-48-3
Catalog No.: 196479
Purity: 95%
MF: C11H17NO5
MW: 243.259
Storage: 2-8 degree Celsius
SMILES: O=C1CC[C@@H](N1C(=O)OC(C)(C)C)C(=O)OC
Catalog No.: 196479
Purity: 95%
MF: C11H17NO5
MW: 243.259
Storage: 2-8 degree Celsius
SMILES: O=C1CC[C@@H](N1C(=O)OC(C)(C)C)C(=O)OC
(R)-1-tert-butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate; CAS No.: 128811-48-3; (R)-1-tert-butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate. PROPERTIES: (R)-1-tert-butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate features molecular formula C11H17NO5 with molecular weight approximately 243.26 g/mol. It generally forms white crystalline solids with a reported melting point of 110-113 C. The compound is moderately hygroscopic and should be stored in a tightly sealed container at room temperature with a desiccant. Safety precautions include using chemical-resistant gloves and eye protection due to potential skin and eye irritation. The ester groups may hydrolyze under acidic or basic conditions. In case of accidental ingestion, immediate medical consultation is advised. APPLICATIONS: (R)-1-tert-butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate functions as a chiral building block for pharmaceutical synthesis. Its oxopyrrolidine structure provides valuable steric effects for receptor binding. In medicinal chemistry, it has been employed in developing novel antibiotic agents targeting bacterial protein synthesis, as reported in pharmaceutical research journals focusing on antibacterial treatments. The dicarboxylate ester groups enable formation of amide bonds for further structural elaboration. Additionally, this compound serves as a building block for chemical libraries used in high-throughput screening, with applications described in combinatorial chemistry literature focusing on diversity-oriented synthesis.
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