Pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate
$250.00
CAS No.: 1666113-04-7
Catalog No.: 193054
Purity: 95%
MF: C12H16N2O3S
MW: 268.338
Storage: 2-8 degree Celsius
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.N1C(CCC1)C#N
Catalog No.: 193054
Purity: 95%
MF: C12H16N2O3S
MW: 268.338
Storage: 2-8 degree Celsius
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.N1C(CCC1)C#N
Pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate; CAS No.: 1666113-04-7; Pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C11H13NOS and a molecular weight of 215.29 g/mol. It exhibits a melting point in the range of 178-182 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as Pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate may cause skin irritation. The cyano group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, Pyrrolidine-2-carbonitrile 4-methylbenzenesulfonate serves as a key intermediate for synthesizing anti-cancer agents, as documented in pharmaceutical research focusing on kinase inhibitors. Its cyano substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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