5-phenylpyrrolidin-2-one
$300.00
CAS No.: 22050-10-8
Catalog No.: 193016
Purity: 95%
MF: C10H11NO
MW: 161.204
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1CCC(N1)=O
Catalog No.: 193016
Purity: 95%
MF: C10H11NO
MW: 161.204
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1CCC(N1)=O
5-phenylpyrrolidin-2-one; CAS No.: 22050-10-8; 5-phenylpyrrolidin-2-one. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C10H11NO and a molecular weight of 165.19 g/mol. It demonstrates a melting point in the range of 178-182 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 5-phenylpyrrolidin-2-one may cause skin irritation. The ketone group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 5-phenylpyrrolidin-2-one serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its phenyl substituent enables improved lipophilicity for enhanced membrane permeability. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrrolidinone ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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