(3R,4R)-tert-butyl 3-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-1-carboxylate
$225.00
CAS No.: 429673-85-8
Catalog No.: 193035
Purity: 95%
MF: C14H25NO5
MW: 287.356
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)[C@@H]1CN(C[C@@H]1O)C(=O)OC(C)(C)C
Catalog No.: 193035
Purity: 95%
MF: C14H25NO5
MW: 287.356
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)[C@@H]1CN(C[C@@H]1O)C(=O)OC(C)(C)C
(3R,4R)-tert-butyl 3-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-1-carboxylate; CAS No.: 429673-85-8; (3R,4R)-tert-butyl 3-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-1-carboxylate. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C14H22N2O4 and a molecular weight of 286.34 g/mol. It demonstrates a melting point in the range of 142-146 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (3R,4R)-tert-butyl 3-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-1-carboxylate may cause skin irritation. The hydroxyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (3R,4R)-tert-butyl 3-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-1-carboxylate serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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