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(2S,4S)-4-methylpyrrolidine-2-carboxylic acid; CAS No.: 6734-41-4; (2S,4S)-4-methylpyrrolidine-2-carboxylic acid. PROPERTIES: (2S,4S)-4-methylpyrrolidine-2-carboxylic acid has molecular formula C6H11NO2 with molecular weight approximately 131.16 g/mol. It typically forms white crystalline solids with a reported melting point of 145-148 C. The compound demonstrates good solubility in water and common polar organic solvents. Proper storage involves keeping in a tightly sealed container at room temperature away from heat and direct sunlight. Safety considerations include using personal protective equipment during handling to prevent skin and eye contact, as it may cause mild irritation. The carboxylic acid group may corrode metals, so compatible storage materials should be used. In case of spillage, absorb with inert material and dispose of properly. APPLICATIONS: (2S,4S)-4-methylpyrrolidine-2-carboxylic acid serves as a chiral building block for pharmaceutical synthesis. Its methyl substituent provides valuable steric effects for receptor binding. In medicinal chemistry, it has been employed in developing novel antidepressant agents targeting serotonin receptors, as documented in psychopharmacology-focused pharmaceutical research journals. The pyrrolidine structure enables specific interactions with target proteins. Additionally, this compound acts as a precursor for veterinary pharmaceuticals, with applications reported in veterinary medicinal chemistry literature focusing on anxiolytic agents.