(2R,4S)-4-amino-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester
$240.00
CAS No.: 348165-60-6
Catalog No.: 193030
Purity: 95%
MF: C10H20N2O2
MW: 200.282
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)N1[C@@H](C[C@@H](C1)N)C
Catalog No.: 193030
Purity: 95%
MF: C10H20N2O2
MW: 200.282
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)N1[C@@H](C[C@@H](C1)N)C
(2R,4S)-4-amino-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester; CAS No.: 348165-60-6; (2R,4S)-4-amino-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C11H21N2O2 and a molecular weight of 217.30 g/mol. It exhibits a melting point in the range of 112-116 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to acidic hydrolysis and should be stored in neutral conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (2R,4S)-4-amino-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester may release irritating vapors upon heating. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, (2R,4S)-4-amino-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrrolidine derivatives. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrrolidine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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