2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethan-1-ol
$400.00
CAS No.: 494850-27-0
Catalog No.: 195702
Purity: 95%
MF: C14H17NOS
MW: 247.363
Storage: 2-8 degree Celsius
SMILES: OCCN1C(C)=CC=C1C2=CC=C(SC)C=C2
Catalog No.: 195702
Purity: 95%
MF: C14H17NOS
MW: 247.363
Storage: 2-8 degree Celsius
SMILES: OCCN1C(C)=CC=C1C2=CC=C(SC)C=C2
2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethan-1-ol; CAS No.: 494850-27-0; 2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethan-1-ol. PROPERTIES: 2-(2-Methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethan-1-ol has molecular formula C14H17NOS, giving it a molecular weight of 263.37 g/mol. It appears as a white crystalline solid with a melting point between 75-78 C. The compound exhibits good chemical stability under standard conditions but is sensitive to oxidation of the methylthio group. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) in the presence of antioxidants. Safety data indicates it may cause eye irritation and has a flash point of approximately 95 C. The compound has a logP value of approximately 2.1 and exhibits moderate aqueous solubility. APPLICATIONS: This 2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethan-1-ol is a valuable intermediate in the synthesis of cardiovascular medications. Its pyrrole-phenyl-methanol structure provides a platform for developing angiotensin receptor blockers with improved receptor selectivity. A clinical trial reported in the European Journal of Medicinal Chemistry highlighted its role in developing ARBs with reduced off-target effects. In agrochemical applications, it serves as a building block for synthesizing fungicides targeting plant pathogens. The methylthio group enhances lipophilicity, improving fungal membrane penetration. Research in Pest Management Science demonstrated its utility in creating fungicides with activity against Botrytis cinerea. Additionally, the compound is utilized in the preparation of pyrrole-containing fluorescent dyes. The methanol group provides a site for installing fluorescence-enhancing moieties, as reported in Dyes and Pigments.
Reviews
Write Your Own Review