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methyl 4-methylpyrimidine-2-carboxylate; CAS No.: 317334-58-0; Methyl 4-methylpyrimidine-2-carboxylate from our pyrimidine series offers orthogonal functionalization sites for parallel synthesis. The C2 ester and C4 methyl group enable sequential modification via hydrolysis and cross-coupling. As a worldwide chemical supplier, we provide pyrimidine derivatives with varied substitution patterns. Our manufacturing process utilizes Biginelli-like cyclocondensation with controlled microwave heating for improved yields. This compound is particularly valuable for dihydrofolate reductase inhibitor research.