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ethyl 6-oxo-1,6-dihydropyrimidine-5-carboxylate; CAS No.: 4786-52-1; This dihydropyrimidine ester highlights ChemShuttle's building blocks for drug discovery in calcium channel modulation. The 6-oxo-1,6-dihydro structure mimics dihydropyridine scaffolds. Our Biginelli reaction optimization achieves high yield. The ethyl ester group allows conversion to amide derivatives for voltage-gated calcium channel blocker development.