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6-methoxypyrimidine-2,4-diamine; CAS No.: 3270-97-1; Specializing in methoxy pyrimidines, ChemShuttle provides 6-methoxypyrimidine-2,4-diamine for antifolate-resistant DHFR inhibition. The methoxy group mimics natural substrates while circumventing resistance mutations, and the diamino motif maintains critical hydrogen bonds. Our cell viability assays include folate rescue experiments.