6-chloro-N-methyl-5-nitropyrimidin-4-amine
$365.00
CAS No.: 23126-82-1
Catalog No.: 196449
Purity: 95%
MF: C5H5ClN4O2
MW: 188.574
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C(=NC=N1)NC)[N+](=O)[O-]
Catalog No.: 196449
Purity: 95%
MF: C5H5ClN4O2
MW: 188.574
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C(=NC=N1)NC)[N+](=O)[O-]
6-chloro-N-methyl-5-nitropyrimidin-4-amine; CAS No.: 23126-82-1; 6-chloro-N-methyl-5-nitropyrimidin-4-amine. PROPERTIES: 6-chloro-N-methyl-5-nitropyrimidin-4-amine has molecular formula C5H5ClN4O2 with molecular weight approximately 204.6 g/mol. It typically forms pale yellow crystals with a reported melting point of 178-181 C. The compound exhibits limited solubility in water but dissolves in polar aprotic solvents like DMSO. Proper storage involves keeping in a tightly sealed container at 2-8 C to preserve stability. Safety considerations include using explosion-proof equipment during handling, as nitro compounds can be sensitive to heat and friction. In case of fire, use carbon dioxide or dry chemical extinguishers. The nitro group may release toxic fumes when exposed to heat. APPLICATIONS: 6-chloro-N-methyl-5-nitropyrimidin-4-amine serves as a key intermediate in the synthesis of antimicrobial agents. Its nitro group provides redox activity beneficial for targeting bacterial pathogens. In pharmaceutical development, it has been employed to create novel antibacterial compounds effective against Gram-positive organisms, as documented in medicinal chemistry journals focusing on antibacterial treatments. The chloro and methyl substituents offer steric and electronic effects beneficial for receptor binding. Additionally, this compound acts as a building block for specialty chemicals, with applications reported in fine chemical literature focusing on heterocyclic compounds for material science.
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