4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine
$320.00
CAS No.: 91717-22-5
Catalog No.: 196323
Purity: 95%
MF: C10H16N4
MW: 192.266
Storage: 2-8 degree Celsius
SMILES: CC1=NC(=NC(=C1)N1CCCCC1)N
Catalog No.: 196323
Purity: 95%
MF: C10H16N4
MW: 192.266
Storage: 2-8 degree Celsius
SMILES: CC1=NC(=NC(=C1)N1CCCCC1)N
4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine; CAS No.: 91717-22-5; 4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine. PROPERTIES: This compound features a 4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine structure, combining a methyl group, a piperidine group, and a pyrimidine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 196.2 g/mol (C9H13N5). The melting point ranges between 100-105 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine structure allows for participation in various reactions, including nucleophilic substitution at the piperidine nitrogen and electrophilic substitution at the pyrimidine ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The methyl group provides steric and electronic effects that influence binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel piperidinopyrimidine derivatives based on the 4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine scaffold.
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