2,4,6-trichloro-5-methylpyrimidine
$500.00
CAS No.: 1780-36-5
Catalog No.: 196456
Purity: 95%
MF: C5H3Cl3N2
MW: 197.452
Storage: 2-8 degree Celsius
SMILES: ClC1=NC(=C(C(=N1)Cl)C)Cl
Catalog No.: 196456
Purity: 95%
MF: C5H3Cl3N2
MW: 197.452
Storage: 2-8 degree Celsius
SMILES: ClC1=NC(=C(C(=N1)Cl)C)Cl
2,4,6-trichloro-5-methylpyrimidine; CAS No.: 1780-36-5; 2,4,6-trichloro-5-methylpyrimidine. PROPERTIES: 2,4,6-trichloro-5-methylpyrimidine features molecular formula C5H3Cl3N2 with molecular weight approximately 278.49 g/mol. It generally appears as a white crystalline solid with a reported melting point of 68-71 C. The compound exhibits limited solubility in water but dissolves in polar organic solvents like DMSO. Proper storage involves keeping in a tightly sealed container at room temperature away from moisture and light. Safety precautions include using respiratory protection when handling powder forms to prevent inhalation, which may cause respiratory irritation. The chloro substituents may release toxic fumes when exposed to heat. In case of accidental ingestion, immediate medical consultation is advised. APPLICATIONS: 2,4,6-trichloro-5-methylpyrimidine functions as a key intermediate in the synthesis of agricultural chemicals (though non-agricultural applications are emphasized here) and pharmaceuticals. Its multiple chloro substituents provide valuable reactivity for nucleophilic aromatic substitution reactions. In pharmaceutical research, it has been utilized to develop novel antimicrobial agents targeting resistant bacterial strains, as reported in medicinal chemistry journals focusing on infectious disease treatments. The methyl group offers steric effects beneficial for receptor binding. Additionally, this compound serves as a building block for specialty chemicals, with applications described in fine chemical literature focusing on heterocyclic compounds for material science.
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