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6-methoxy-3H,4H-pyrido[3,4-d]pyrimidin-4-one
$338.00
CAS No.: 183741-98-2
Catalog No.: 192962
Purity: 95%
MF: C8H7N3O2
MW: 177.163
Storage: 2-8 degree Celsius
SMILES: COC1=CC2=C(N=CNC2=O)C=N1
Catalog No.: 192962
Purity: 95%
MF: C8H7N3O2
MW: 177.163
Storage: 2-8 degree Celsius
SMILES: COC1=CC2=C(N=CNC2=O)C=N1
6-methoxy-3H,4H-pyrido[3,4-d]pyrimidin-4-one; CAS No.: 183741-98-2; 6-methoxy-3H,4H-pyrido[3,4-d]pyrimidin-4-one. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C9H7N3O2 and a molecular weight of 193.17 g/mol. It exhibits a melting point in the range of 178-182 C and demonstrates good solubility in polar solvents such as dimethylformamide and dimethyl sulfoxide. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 6-methoxy-3H,4H-pyrido[3,4-d]pyrimidin-4-one may release irritating vapors upon heating. The methoxy group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 6-methoxy-3H,4H-pyrido[3,4-d]pyrimidin-4-one serves as a key intermediate for synthesizing anticancer agents, as documented in pharmaceutical research focusing on kinase inhibitors. Its methoxy substituent enables improved solubility in biological systems for enhanced bioavailability. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyridopyrimidinone ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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