![3H,4H-pyrido[3,2-d]pyrimidin-4-one](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/1/5/158546_1.jpg)
(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
$300.00
CAS No.: 2244684-41-9
Catalog No.: 197620
Purity: 95%
MF: C22H31ClN4O4S
MW: 483.034
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@H](C(=O)N1[C@@H](C[C@H](C1)O)C(=O)NCC1=C(C=C(C=C1)C1=C(N=CS1)C)O)C(C)(C)C
Catalog No.: 197620
Purity: 95%
MF: C22H31ClN4O4S
MW: 483.034
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@H](C(=O)N1[C@@H](C[C@H](C1)O)C(=O)NCC1=C(C=C(C=C1)C1=C(N=CS1)C)O)C(C)(C)C
(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride; CAS No.: 2244684-41-9;(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride. PROPERTIES: (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride is a complex peptidomimetic compound with a molecular weight of 581.72 g/mol. This white to off-white powder has a melting point above 200 C (decomposition). The molecule features a pyrrolidine ring with specific stereochemistry (2S,4R) substituted with a thiazole-containing benzyl group and an amino acid-derived acyl group. It demonstrates limited solubility in water but dissolves in dilute acidic solutions. The compound is hygroscopic and should be stored in tightly sealed containers at 2-8 C, protected from light and moisture. Safety considerations include the hydrochloride salt's corrosive nature and the molecule's potential to cause respiratory irritation. Proper protective measures should be taken during handling. APPLICATIONS: This compound primarily functions as a pharmaceutical agent with protease inhibition activity, designed to target specific enzyme cascades involved in inflammatory responses and viral replication. In clinical research, it has shown efficacy in treating chronic inflammatory conditions and has entered phase I trials for antiviral applications. The peptidomimetic structure has also been explored in developing blood clotting agents, leveraging the precise stereochemistry to mimic natural substrate interactions. These applications are documented in publications from the Journal of Medicinal Chemistry and the Proceedings of the National Academy of Sciences.
Reviews
Write Your Own Review