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tert-butyl 4-(6-formylpyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carboxylate
$435.00
CAS No.: 1258638-43-5
Catalog No.: 171970
Purity: 95%
MF: C17H22N4O3
MW: 330.388
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CCC(CC1)C1=NN2C=C(C=O)C=NC2=C1
Catalog No.: 171970
Purity: 95%
MF: C17H22N4O3
MW: 330.388
Storage: 2-8 degree Celsius
SMILES: CC(C)(C)OC(=O)N1CCC(CC1)C1=NN2C=C(C=O)C=NC2=C1
tert-butyl 4-(6-formylpyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carboxylate; CAS No.: 1258638-43-5; Operating as a Leading Chemicals Distributor, ChemShuttle supplies tert-butyl 4-(6-formylpyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carboxylate. This aldehyde-functionalized heterocycle serves as a key intermediate for PROTAC synthesis. The formyl group enables conjugation to E3 ligase ligands via reductive amination, while the Boc-protected piperidine provides a handle for linker optimization. Applications include targeted protein degradation in oncology and neurodegenerative disease research. ChemShuttle provides SPR binding data for common E3 ligases, facilitating rational design of ternary complexes. Custom services include preparation of bifunctional linkers with varying PEG lengths and rigidity.
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