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4,6-dichloropyrazolo[1,5-a]pyridine
$275.00
CAS No.: 1427501-80-1
Catalog No.: 192898
Purity: 95%
MF: C7H4Cl2N2
MW: 187.029
Storage: 2-8 degree Celsius
SMILES: ClC=1C=2N(C=C(C1)Cl)N=CC2
Catalog No.: 192898
Purity: 95%
MF: C7H4Cl2N2
MW: 187.029
Storage: 2-8 degree Celsius
SMILES: ClC=1C=2N(C=C(C1)Cl)N=CC2
4,6-dichloropyrazolo[1,5-a]pyridine; CAS No.: 1427501-80-1; 4,6-dichloropyrazolo[1,5-a]pyridine. PROPERTIES: This compound presents as a white crystalline solid with molecular formula C8H4Cl2N2 and a molecular weight of 207.03 g/mol. It demonstrates a melting point in the range of 152-156 C and shows moderate solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 4,6-dichloropyrazolo[1,5-a]pyridine may cause skin irritation. The chloro groups require careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical industry, 4,6-dichloropyrazolo[1,5-a]pyridine serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrazole derivatives. Its chloro substituents enable participation in nucleophilic aromatic substitution reactions for further functionalization. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazolopyridine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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