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1H-pyrazolo[3,4-c]pyridine-7-carboxylic acid
$400.00
CAS No.: 1140239-98-0
Catalog No.: 192889
Purity: 95%
MF: C7H5N3O2
MW: 163.136
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C1=C(N=CC2)C(=O)O
Catalog No.: 192889
Purity: 95%
MF: C7H5N3O2
MW: 163.136
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C1=C(N=CC2)C(=O)O
1H-pyrazolo[3,4-c]pyridine-7-carboxylic acid; CAS No.: 1140239-98-0; 1H-pyrazolo[3,4-c]pyridine-7-carboxylic acid. PROPERTIES: This compound presents as a white crystalline solid with molecular formula C8H5N3O2 and a molecular weight of 179.14 g/mol. It demonstrates a melting point in the range of 230-234 C and shows moderate solubility in polar solvents such as dimethylformamide and dimethyl sulfoxide. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 1H-pyrazolo[3,4-c]pyridine-7-carboxylic acid may release irritating vapors upon heating. The carboxylic acid group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 1H-pyrazolo[3,4-c]pyridine-7-carboxylic acid serves as a key intermediate for synthesizing anticancer agents, as documented in pharmaceutical research focusing on kinase inhibitors. Its carboxylic acid substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrazolopyridine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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