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1H-pyrazolo[3,4-b]pyridin-6-ol
$225.00
CAS No.: 61514-61-2
Catalog No.: 192909
Purity: 95%
MF: C6H5N3O
MW: 135.126
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C1=NC(=CC2)O
Catalog No.: 192909
Purity: 95%
MF: C6H5N3O
MW: 135.126
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C1=NC(=CC2)O
1H-pyrazolo[3,4-b]pyridin-6-ol; CAS No.: 61514-61-2; 1H-pyrazolo[3,4-b]pyridin-6-ol. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C7H5N3O and a molecular weight of 147.13 g/mol. It demonstrates a melting point in the range of 198-202 C and shows moderate solubility in polar solvents such as water and methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 1H-pyrazolo[3,4-b]pyridin-6-ol may release irritating vapors upon heating. The hydroxyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 1H-pyrazolo[3,4-b]pyridin-6-ol serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrazolopyridine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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