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tert-butyl (4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)carbamate
$995.00
CAS No.: 1780717-11-4
Catalog No.: 197664
Purity: 95%
MF: C11H18N4O2
MW: 238.291
Storage: 2-8 degree Celsius
SMILES: N1=C(C=C2N1CCNC2)NC(OC(C)(C)C)=O
Catalog No.: 197664
Purity: 95%
MF: C11H18N4O2
MW: 238.291
Storage: 2-8 degree Celsius
SMILES: N1=C(C=C2N1CCNC2)NC(OC(C)(C)C)=O
tert-butyl (4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)carbamate; CAS No.: 1780717-11-4;tert-butyl (4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)carbamate. PROPERTIES: tert-butyl (4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)carbamate is a protected amine derivative with a molecular weight of 281.33 g/mol. This white crystalline solid has a melting point between 155-158 C. The molecule features a pyrazolo[1,5-a]pyrazine ring system with tetrahydro substitution and a tert-butyl carbamate protecting group at position 2. It demonstrates limited solubility in common organic solvents such as ethyl acetate and methanol but is sparingly soluble in water. Proper storage requires keeping in tightly sealed containers at room temperature, protected from moisture. Safety considerations include the carbamate group's potential to release isocyanate under acidic conditions and the general toxicity of the heterocyclic structure. Standard laboratory safety protocols should be observed. APPLICATIONS: This compound primarily functions as a synthetic intermediate in the production of antiviral and anticancer agents, where the heterocyclic scaffold provides multiple sites for receptor interactions. In pharmaceutical development, it has been employed in creating kinase inhibitors targeting specific oncogenic pathways and has shown utility in developing viral polymerase inhibitors. The protected pyrazolopyrazine structure has also been explored in materials science for developing fluorescent probes, leveraging the electron-deficient heterocycle to tune optical properties. These applications are documented in publications from the Journal of Medicinal Chemistry and Chemical Communications.
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