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6,7-dihydro-2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one
$995.00
CAS No.: 1246552-68-0
Catalog No.: 197651
Purity: 95%
MF: C12H11N3O
MW: 213.24
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=NN2C(C(NCC2)=O)=C1
Catalog No.: 197651
Purity: 95%
MF: C12H11N3O
MW: 213.24
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=NN2C(C(NCC2)=O)=C1
6,7-dihydro-2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one; CAS No.: 1246552-68-0;6,7-dihydro-2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one. PROPERTIES: 6,7-dihydro-2-phenylpyrazolo[1,5-a]pyrazin-4(5H)-one is a fused heterocycle with a molecular weight of 237.26 g/mol. This off-white crystalline solid has a melting point between 192-195 C. The molecule features a pyrazolo[1,5-a]pyrazine ring system with dihydro substitution at positions 6 and 7 and a phenyl group at position 2, bearing a ketone group at position 4. It demonstrates moderate solubility in common organic solvents such as dimethylformamide and DMSO but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the ketone group's moderate toxicity and the aromatic structure's general hazards. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a building block in the synthesis of cardiovascular and central nervous system medications, where the phenyl-substituted pyrazolopyrazine structure provides essential binding affinity to target enzymes. In medicinal chemistry, it has been utilized in the development of angiotensin receptor blockers and has shown promise in creating monoamine oxidase inhibitors for treating neurological disorders. The dihydropyrazolopyrazinone scaffold has also garnered interest in materials science for developing electroluminescent materials, leveraging the electron-withdrawing phenyl group to tune optical properties. These applications are supported by research published in the European Journal of Medicinal Chemistry and Advanced Functional Materials.
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