4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine; CAS No.: 1785544-01-5;4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine. PROPERTIES: 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine is a heterocyclic amine with a molecular weight of 175.20 g/mol. This white crystalline solid has a melting point between 185-188 C. The molecule features a pyrazolo[1,5-a]pyrazine ring system with tetrahydro substitution and an amine group at position 2. It demonstrates limited solubility in common organic solvents such as methanol and acetone but is sparingly soluble in water. Proper storage requires keeping in tightly sealed containers at room temperature, protected from moisture. Safety considerations include the amine group's basicity and the heterocycle's general toxicity. Standard laboratory safety protocols should be observed. APPLICATIONS: This compound primarily serves as a building block in the synthesis of agrochemicals and pharmaceuticals, where the amine group provides sites for further functionalization. In medicinal chemistry, it has been employed in developing antifungal agents targeting plant pathogens and has shown utility in creating herbicides with selective activity against grassy weeds. The tetrahydropyrazolopyrazine structure has also been explored in materials science for developing chiral ligands in asymmetric catalysis, leveraging the amine group's stereoelectronic effects. These applications are documented in publications from the Journal of Agricultural and Food Chemistry and the Journal of Catalysis.