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5-tert-butyl 2-ethyl 7,8-dihydro-4H-Pyrazolo[1,5-A][1,4]diazepine-2,5(6H)-dicarboxylate
$365.00
CAS No.: 1250997-22-8
Catalog No.: 197780
Purity: 95%
MF: C15H23N3O4
MW: 309.366
Storage: 2-8 degree Celsius
SMILES: N1=C(C=C2N1CCCN(C2)C(=O)OC(C)(C)C)C(=O)OCC
Catalog No.: 197780
Purity: 95%
MF: C15H23N3O4
MW: 309.366
Storage: 2-8 degree Celsius
SMILES: N1=C(C=C2N1CCCN(C2)C(=O)OC(C)(C)C)C(=O)OCC
5-tert-butyl 2-ethyl 7,8-dihydro-4H-Pyrazolo[1,5-A][1,4]diazepine-2,5(6H)-dicarboxylate; CAS No.: 1250997-22-8;5-tert-butyl 2-ethyl 7,8-dihydro-4H-Pyrazolo[1,5-A][1,4]diazepine-2,5(6H)-dicarboxylate. PROPERTIES: 5-tert-butyl 2-ethyl 7,8-dihydro-4H-Pyrazolo[1,5-A][1,4]diazepine-2,5(6H)-dicarboxylate is a diesterified heterocycle with a molecular weight of 356.41 g/mol. This white crystalline solid has a melting point between 100-103 C. The molecule features a pyrazolo[1,5-A][1,4]diazepine ring system with dihydro substitution at positions 7 and 8, a tert-butyl ester at position 5, and an ethyl ester at position 2. It demonstrates moderate solubility in common organic solvents such as methanol and acetone but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the ester groups' flammability and the heterocycle's general toxicity. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily functions as a synthetic intermediate in the production of pharmaceuticals and specialty chemicals, where the diesterified pyrazolodiazepine structure provides versatile sites for cross-coupling and nucleophilic substitution reactions. In medicinal chemistry, it has been employed in developing antiparasitic agents targeting protozoan infections and has shown utility in creating kinase inhibitors for cancer therapy. The pyrazolodiazepine-dicarboxylate structure has also been explored in materials science for developing nonlinear optical materials, leveraging the polarizable ester groups to enhance optical properties. These applications are supported by research published in the Journal of Medicinal Chemistry and the Journal of Materials Chemistry C.
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