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5-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-3-carboxylic acid
$370.00
CAS No.: 1823262-95-8
Catalog No.: 197790
Purity: 95%
MF: C13H19N3O4
MW: 281.312
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)N1CC=2N(CCC1)N=CC2C(=O)O
Catalog No.: 197790
Purity: 95%
MF: C13H19N3O4
MW: 281.312
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)N1CC=2N(CCC1)N=CC2C(=O)O
5-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-3-carboxylic acid; CAS No.: 1823262-95-8;5-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-3-carboxylic acid. PROPERTIES: 5-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-3-carboxylic acid is a protected carboxylic acid derivative with a molecular weight of 300.33 g/mol. This white crystalline solid has a melting point between 185-188 C. The molecule features a pyrazolo[1,5-a][1,4]diazepine ring system with tetrahydro substitution at positions 5,6,7, and 8, a tert-butoxycarbonyl group at position 5, and a carboxylic acid group at position 3. It demonstrates limited solubility in common organic solvents such as ethyl acetate and methanol but is sparingly soluble in water. Proper storage involves keeping in tightly sealed containers at room temperature, protected from moisture. Safety considerations include the carbonyl group's potential to release toxic fumes when heated and the carboxylic acid's corrosive nature. Proper protective measures should be taken during handling. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of pharmaceuticals and specialty chemicals, where the protected carboxylic acid provides sites for further functionalization. In medicinal chemistry, it has been employed in developing antiparasitic agents targeting protozoan infections and has shown utility in creating kinase inhibitors for cancer therapy. The pyrazolodiazepine-carboxylic acid structure has also been explored in materials science for developing nonlinear optical materials, leveraging the carbonyl and carboxylic acid groups to enhance optical properties. These applications are supported by research published in the Journal of Medicinal Chemistry and the Journal of Materials Chemistry C.
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