methyl 5-cyano-1-methyl-1H-pyrazole-3-carboxylate
$300.00
CAS No.: 203792-51-2
Catalog No.: 192873
Purity: 95%
MF: C7H7N3O2
MW: 165.152
Storage: 2-8 degree Celsius
SMILES: C(#N)C1=CC(=NN1C)C(=O)OC
Catalog No.: 192873
Purity: 95%
MF: C7H7N3O2
MW: 165.152
Storage: 2-8 degree Celsius
SMILES: C(#N)C1=CC(=NN1C)C(=O)OC
methyl 5-cyano-1-methyl-1H-pyrazole-3-carboxylate; CAS No.: 203792-51-2; methyl 5-cyano-1-methyl-1H-pyrazole-3-carboxylate. PROPERTIES: This compound presents as a colorless to pale yellow crystalline solid with molecular formula C8H7N3O2 and a molecular weight of 181.16 g/mol. It exhibits a melting point in the range of 108-112 C and demonstrates moderate solubility in common organic solvents like methanol and dichloromethane. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as methyl 5-cyano-1-methyl-1H-pyrazole-3-carboxylate may release toxic fumes upon heating. The cyano group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, methyl 5-cyano-1-methyl-1H-pyrazole-3-carboxylate serves as a key intermediate for synthesizing anticancer agents, as documented in pharmaceutical research focusing on kinase inhibitors. Its cyano substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through coupling reactions. Academic studies have explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazole ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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