3-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine
$325.00
CAS No.: 1186609-16-4
Catalog No.: 192866
Purity: 95%
MF: C7H11N3O
MW: 153.185
Storage: 2-8 degree Celsius
SMILES: O1CC(CC1)C1=NNC(=C1)N
Catalog No.: 192866
Purity: 95%
MF: C7H11N3O
MW: 153.185
Storage: 2-8 degree Celsius
SMILES: O1CC(CC1)C1=NNC(=C1)N
3-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine; CAS No.: 1186609-16-4; 3-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine. PROPERTIES: This compound appears as a colorless to pale yellow oil with molecular formula C8H13N3O and a molecular weight of 167.21 g/mol. It has a boiling point in the range of 220-225 C at 760 mmHg and demonstrates good solubility in common organic solvents like ethyl acetate and tetrahydrofuran. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage conditions include maintaining in tightly sealed amber containers at temperatures below 10 C, protected from light and oxygen. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 3-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine may release flammable vapors. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In pharmaceutical research, 3-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine serves as a key intermediate for synthesizing kinase inhibitors, as documented in medicinal chemistry literature focusing on cancer therapeutics. Its tetrahydrofuran substituent enables improved membrane permeability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic studies have explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrazole ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials chemistry, as evidenced by structural chemistry publications.
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